Magnetic Sensor Particles: a New Tool for the Determination of Oxygen in Microfluidics

We present the application of multifunctional nanoparticles in microfluidic devices. The particles have an oxygen sensing function and can be collected by magnetic forces at any desired position in the microfluidic channels. The nanoparticles are prepared by a simple precipitation technique. Read-out of the in situ generated sensor spots was performed applying luminescence lifetime and ratio metric imaging. The formation of multiple sensor spots in one channel for the parallel measurement of various parameters is shown and the respiration of E. coli culture assembly illustrated.